Why Angel System?
Operator controls platelet concentration!
With one-button automation, clinicians enter the blood volume to be processed and press the touch screen “start” button to operate in fully automatic mode. More experienced clinicians may create customized spin protocols to suit different procedures and patient populations.
Portability!
Data export and print options may be used to archive procedural and patient data.
Compact design makes the system easy to move from one clinical setting to another: OR, hospital, outpatient clinic, or physician’s office.
Windows®-based touch screen dashboard monitors volumes of all blood components—PRP, PPP, RBC—throughout every step of the process cycle.
High platelet yields, reproducible results!
The Angel fully engineered software program precisely controls blood component separation to produce a consistently high percentage of functional platelets.
Angel System advantage: High percentage of functional platelets
|
Whole Blood (60ml), PRP* (diluted to 6ml) |
N=5 unique donors |
%Platelet Aggregation
ADP Activation |
%Platelet Aggregation
Collagen Activation |
|
Mean ±S.D. |
97.4 ±0.7 |
93.2% ±2.7 |
|
Proprietary dual-spin algorithms automatically adjust the Angel separation parameters to deliver reproducible platelet yields at any whole blood volume between 40-180ml.
Broad range of platelet concentrations!
Angel produces a highly concentrated PRP sample using a 7% hematocrit setting (=18x baseline). Following the Standard PPP Dilution Protocol, Angel delivers a PRP preparation containing concentrated platelets approximately 6x-8x baseline. Custom protocols offer clinicians a broad range of procedure-specific options with a user-defined range of platelet and leukocyte concentrations.
Broad range of hematocrit settings!
Angel hematocrit setting |
Reduction in neutrophil count1,2 |
Platelet Concentration x baseline2 |
7% |
80% |
x 18 (diluted to 7x by adding PPP) |
2% |
99% |
x 12 (diluted to 5x by adding PPP) |
Certain leukocyte populations such as neutrophils have densities that overlap that of red blood cells while others such as B and T lymphocytes reside in the buffy-coat fraction that floats on the red cell pack.
To produce a neutrophil-depleted, platelet-rich PRP, select the 2% hematocrit setting.
Further decreases and increases in total leukocytes in the final PRP, can be achieved by adjusting the Angel hematocrit settings between 0-25%. |